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#neuro

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Niko Sirmpilatze

🚀 Some exciting news! Our team is taking part in Google Summer of Code, which is a remote, asynchronous, global opportunity.

This is a fantastic chance for someone to get paid to contribute to "movement" or our other open-source projects in neuroscience and animal behaviour.

If you know someone who might be interested, please share widely! 🌍

Full details are here:
neuroinformatics.dev/get-invol

neuroinformatics.devGoogle Summer of Code — NIU
#neuroscience#neuro#behaviour
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Neurofrontiers

We're just migrated from another instance, so here is our (re)introduction:

Neurofrontiers is a bilingual blog about interesting neuroscience topics that tries to be accessible to the broader public while still maintaining scientific accuracy. It's run by a team of two people: a computational neuroscientist, and a graphic designer. We think that being on social media allows us to stay up-to-date with the most recent discussions in science and hope to be able to connect with like-minded individuals.

Posting interests below so we show up in mutual searches:
#neuroscience #brain #mentalhealth #neuro #neurology #depression #medicine #health #covid #neuropsychology #psychiatry #psychology #genomics #genetics #virology #biology #chemistry #biochem #physics #history #geology #astronomy #research #MedTwitter #ScienceTwitter #academia #stem #science #scicomm

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Daniel Prieto

El #iibce on fire (para ser justos con la fabulosa foto de Gabriela Fabbiani).
El equipo de divulgación lo hizo otra vez!
Ahora, con un trabajo de mis compañerxs de labo, liderado por dos notables #mujeresenciencia en un proyecto que nos enorgullece mucho.
Les presento al receptor p2x7 y su potencial para ayudar a regenerar el sistema nervioso.

gub.uy/ministerio-educacion-cu

#neuro #neurociencia #uruguay #biologia #investigacion #ciencia #divulgacion #sistemanerviosocentral #WingsForLifeWorldRun #womeninstem #latinamerica @SocNeuroUy

Imagen que muestra células del canal central de la médula espinal de ratón (abajo), migrando hacia el sitio de la lesión (arriba). Se ha aplicado una escala de falso color que da el aspecto de una fogata, donde los núcleos ovoides de las células se ven más intensos como brasas en la parte inferior, y las prolongaciones de las células aparecen más claras como llamas. Imagen de microscopía láser confocal tomada por Gabriela Fabbiani en el Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.
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Daniel Prieto

El cerebro dinámico. Viaje en el tiempo hacia los secretos del cerebro

Otra bella nota de #divulgacion de nuestro trabajo sobre la #biologia del #desarrollo del #cerebro. Usando la #mosca #drosophilamelanogaster estudiamos un mecanismo de percepción de #oxígeno relacionado con el tamaño del cerebro.

Colaboración entre el #iibce de #Uruguay y la Universidad de #Friburgo en #Suiza.

#neurociencia #biologíadeldesarrollo #celulasmadre #neurobiologia #biologíacelular #drosophila #insectos #ciencia #microscopia #neuro #investigacion
#divulgacioncientifica @SocNeuroUy

gub.uy/ministerio-educacion-cu

Ministerio de Educación y CulturaEl cerebro dinámico. Viaje en el tiempo hacia los secretos del cerebroA lo largo de la historia de nuestro planeta, los insectos han experimentado cambios sorprendentes en su tamaño. Cuando la atmósfera contenía más
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Daniel Prieto

:atom: Oportunidad de #trabajo :atom:
Llamado a #postdoc en #Uruguay en un proyecto de #investigacion:

The role of connexins in self-repair induced by endogenous spinal progenitors", financiado por Wings for Life Spinal Cord Research Foundation (Austria, wingsforlife.com/uk/research/t).

Supportive & inclusive environment :mrgreen:.

Si alguien está pensando en presentarse y mudarse a Uruguay, o quiere saber más, no dude en contactarse.

gub.uy/ministerio-educacion-cu

Wings for LifeWings for Life: Funding science to cure spinal cord injuryWe are a not-for-profit foundation. Our mission is to find a cure for spinal cord injury. We fund life-changing research with your donation. Please support us.
#ciencia#jobs#jobsinscience
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Dr. Marie McNeely

In this new podcast episode, Dr. Lin Tian discusses her research creating molecular tools to study neural circuits, understand neurological disorders, and develop better therapeutics. She also provides insight into her career path, recent successes, advice, and more.

peoplebehindthescience.com/dr-

People Behind the Science Podcast · 757: Dr. Lin Tian: Developing Molecular Biotechnology Tools for Neural Dynamics Research and Novel Therapeutics - People Behind the Science PodcastListen to the Episode Below (0:43:22) 0.75x 1x 1.25x 1.5x 2x 0:000:43:22 757: Dr. Lin Tian: Developing Molecular Biotechnology Tools for Neural Dynamics Research and Novel Therapeutics Apple PodcastsGoogle PodcastsSpotifyPlayer EmbedShare Leave a ReviewListen in a New WindowDownloadSoundCloudStitcherSubscribe on AndroidSubscribe via RSS Dr. Lin Tian is a Scientific Director at the Max Planck Florida Institute […]
#neuroscience#neuro#biology
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NiftyNeuro

#science #neuro Knowing beforehand who's going to respond to a treatment is a key question. In this study they used resting state EEG to predict responses to tDCS + cognitive intervention, in a sample of 70 individuals with Alzheimer's Disease. ("predict" is as usual a misnomer; they already had the outcome data and used ML techniques to predict the outcome for each individual. It's better than a regression in that sense, and promising to try for real, prospectively.)

frontiersin.org/articles/10.33

Table 2 shows Brain regions with the highest predictive scores for response to neurostimulation combined with cognitive stimulation, in AD patients. There are three columns: the left is the brain region, which is frontal, central/parietal, temporal, and occipital. The second column is the average amplitude in microvolts, all less than 1. the average amplitude refers to the mean of the patterns of the brain activity at different frequencies--delta, theta, beta, and gamma-for each brain region. The Third column is Feature Importance, which is .074 for frontal, .069 for central/parietal, .022 for temporal, and .051 for Occipital. The range of feature importance values in a Random Forest Model can vary from 0 to 1 with larger values indicating the features that are more important for accurate predictions.
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NiftyNeuro

#science #neuro This is an excellent collection and review of thermal illusions in skin sensations! They cover the history (those wacky 1800s!) as well as current understanding of the different receptors, and then the illusions--all the tricks you can play on your skin's sense of heat. 😄 There used to be an excellent example of that at the Exploratorium in San Fran., where a metal coil felt first cold and then *extremely* hot, which is a version of these illusions.

frontiersin.org/articles/10.33

A picture of the thermal referral illusion. On the left, there is warm stimulation on the pads of the index and ring fingers, but neutral stimulation on the middle finger. On the right is an image of what is felt: all three fingers feel the same temperature and it is not as warm as the actual temperature under the index and ring fingers.
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NiftyNeuro

#science #neuro If you're into consciousness and how it might arise in humans, you might want to skim this research topic! The editorial pre-print is linked below.

Electromagnetic Field Theories of Consciousness: Opportunities and Obstacles -- "... in part, a celebration of the 30th anniversary of the game-changing “neural correlates of consciousness” concept, first proposed as part of Crick and Koch’s 1990 “neurobiological theory of consciousness.”"

frontiersin.org/articles/10.33

FrontiersEditorial for Electromagnetic field theories of consciousness research topicOur research topic was, in part, a celebration of the 30th anniversary of the gamechanging "neural correlates of consciousness" concept, first proposed as part of Crick and Koch's 1990 "neurobiological theory of consciousness." After now thirty-three years of research and theory-building, however, scholars in the science of consciousness are perhaps not much closer to a widely accepted theory of consciousness.An electromagnetic (EM) field theory of consciousness attempts to explain the nature of consciousness and its relationship to matter in terms of fundamental EM fields and their dynamics. EM field theories view brain waves (delta, theta, etc.) and related EM fields as causally potent and functionally relevant to consciousness and the workings of the brain. EM field theories are a promising and growing subset of consciousness theories.These theories originally emerged because they drew on considerable experimental evidence and provided potential solutions to traditional neuroscience's well-known problems. For example, how does the unity of consciousness arise from the functioning of billions of neurons and glia?It is worth noting that most physicalist theories of consciousness boil down to a type of EM field theory of consciousness, whether or not this is acknowledged. This is the case because the atomic basis of the material comprising our brains, our bodies, and our biosphere is intrinsically electromagnetic. Other fundamental forces -gravity and the strong and weak n...
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NiftyNeuro

#science #neuro For those who do neuroimaging, this is a piece from an expert in neuroimaging on what to look for in resting state fMRI to make sure you're working with high quality data. This is a constant debate, and it's worth seeing the latest data and arguments.

"Quality control procedures and metrics for resting-state functional MRI"--there are 11 articles in the research topic, all on fMRI quality control for research studies.

frontiersin.org/articles/10.33

Five time series graphs showing different estimates of head movement during the scan of a given subject. Green bars starting at frame 110 to the end on all graphs show that the head motion occurred in those time points. These are estimated head motion realignment parameters for subject sub-102, who had the largest maximum volume-to-volume motion of 6.5 mm. However, this motion occurred at the end of the run, so the effects of this motion can be eliminated by censoring the last few time points.
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NiftyNeuro

#science #neuro
This is a common theme: the importance of daily exercise in aging healthfully.

"Our findings confirmed that physical activity was associated with fewer complaints in attention (R2 = 0.35) and executive functions (R2 = 0.37) but not in memory storage (R2 = 0.28). Based on the effect sizes (R2) our results support the idea that physical activity represents a critical factor in explaining some working memory complaints."

Get out there and go dancing! 😄

frontiersin.org/articles/10.33

FrontiersThe contribution of being physically active to successful agingGrowing old involves changes in physical, psychological, and cognitive functions. Promoting physical and mental health has become one of the priorities for an aging population. Studies have demonstrated the benefits of engaging in regular physical activity. Here, we aimed to understand the relationships between physical activity and working memory complaints in attention, memory storage, and executive functions. We hypothesized that physical activity was negatively associated with complaints in working memory domains after controlling for socio-demographics and distress factors, such as anxiety, stress, and depression. Two hundred and twenty-three individuals aged between 65 and 100 years (74.84; SD = 7.74; 133 males) without self-reported neurological and/or psychiatric disorders completed a questionnaire on socio-demographic, with questions on physical activity and the Italian version of the working memory questionnaire (WMQ) and the DASS-21 measuring anxiety, stress, and depression. Results from three linear regression models showed that low physical activity was associated with complaints in attention (R2 = 0.35) and executive functions (R2 = 0.37) but not in memory storage (R2 = 0.28). Notably, age, gender, and total emotional distress (DASS score) were significant in all regression models. Our results suggested regular physical activity, even just walking, is crucial for maintaining efficient cognitive function. Theoretical and practical implications for engaging in ...
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NiftyNeuro

#science #neuro
This is fascinating--a case report in focal epilepsy where the seizures are preceded by the inability to speak (aphasia), but the origin of the seizures is in the right hemisphere, and it's only once it spreads to the left hemisphere that the aphasia and seizure actually occurs! (see image)

And they were able to treat it once they figured that out. The assumption would be the origin is on the left given the speech issues, but that was not the case.

frontiersin.org/articles/10.33

Seizure onset and propagation in stereo-EEG. Figure A on the left is two side views of a brain, showing the locations of Stereo-EEG implantation: right hemisphere (black background, upper image) and left hemisphere (blue background, lower image). The locations center around the temporal lobe, from frontal areas along the temporal lobe to the more posterior areas. (B) A time plog showing Stereo-EEG recording of spontaneous seizure recordings from all the implanted electrodes. It shows an increase of interictal spike on the contacts electrodes that explore the posterior portion of the right superior temporal gyrus (labeled asW4-5, W9-10, U4-5, T3-4), followed by low-voltage fast activity in the same region (indicated by a red star). One and a hlf seconds later, the discharge spreads to the left homologous region (W′7–8, red arrow). Then, after 14 s, it also involves the right temporal pole (I4-5) and hippocampus (C2-3), and immediately it propagates to the left homologous regions (I′7–8, B′2–3). After 26 s from the right ictal onset, a new ictal discharge arises in the left hippocampus (B′2–3) and spreads after 3 s into the right hippocampus (B2-3). The right side of the time course plot shows all electrodes' signals wildly oscillating with spontaneous electrical neural activity.
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NiftyNeuro

#science #neuro Busted your Anterior Cruciate Ligament and had it reconstructed? This study is for you! Turns out there's an effect in the cortex for that, with greater activity in the motor cortex for moving the involved knee.

"In the ACLR group, the involved limb had unique activation in areas responsible for sensory integration, potentially indicating a compensatory neural strategy to maintain motor control...."

(full text in the link)
frontiersin.org/articles/10.33

FrontiersOrganization of sensorimotor activity in anterior cruciate ligament reconstructed individuals: an fMRI conjunction analysisIntroductionAnterior cruciate ligament reconstruction (ACLR) is characterized by persistent involved limb functional deficits that persist for years despite rehabilitation. Previous research provides evidence of both peripheral and central nervous system adaptations following ACLR. However, no study has compared functional organization of the brain for involved limb motor control relative to the uninvolved limb and healthy controls. The purpose of this study was to examine sensorimotor cortex and cerebellar functional activity overlap and non-overlap during a knee motor control task between groups (ACLR and control), and to determine cortical organization of involved and uninvolved limb movement between groups.MethodsEighteen participants with left knee ACLR and 18 control participants performed a knee flexion/extension motor control task during functional magnetic resonance imaging (fMRI). A conjunction analysis was conducted to determine the degree of overlap in brain activity for involved and uninvolved limb knee motor control between groups.ResultsThe ACLR group had a statistically higher mean percent signal change in the sensorimotor cortex for the involved > uninvolved contrast compared to the control group. Brain activity between groups statistically overlapped in sensorimotor regions of the cortex and cerebellum for both group contrasts: involved > uninvolved and uninvolved > involved. Relative to the control group, the ACLR group uniquely activated superior pariet...
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Theresa Desrochers

🚨 Job Alert: Deadline Extended to Jan 1 🚨
Need some extra time to apply after SFN/the holiday? We got you. Please share.

Come be my colleague!

The Dept of Neuroscience at Brown University is hiring! A tenure-track Assistant Professor position is available for neuroscientists focusing in any topical area. If you wish to join our inclusive community of dedicated scholars & educators, info & apply @ apply.interfolio.com/132440

Adult mouse cerebellum with Purkinje neurons labeled in red and axons labeled in green (Image by A. Tulloch, Jaworski laboratory)
#neuroscience#neuro#job
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