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#genetics

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**Medieval genomes from eastern Iberia illuminate the role of Morisco mass deportations in dismantling a long-standing genetic bridge with North Africa**

“_For the first time, we also demonstrate the persistence of North African ancestry in a Christian cemetery until the seventeenth century, in addition to evidence of slave trafficking from North Africa._”

Oteo-Garcia, G., Silva, M., Foody, M.G.B. et al. Medieval genomes from eastern Iberia illuminate the role of Morisco mass deportations in dismantling a long-standing genetic bridge with North Africa. Genome Biol 26, 108 (2025). doi.org/10.1186/s13059-025-035.

#OpenAccess #OA #Research #Biology #Science #Archaeology #Archaeodons #Genetics #Genomes #History #Medieval #Iberia #Academia #Academics @science @archaeodons

BioMed CentralMedieval genomes from eastern Iberia illuminate the role of Morisco mass deportations in dismantling a long-standing genetic bridge with North Africa - Genome BiologyBackground The Islamic influence on the Iberian Peninsula left an enduring cultural and linguistic legacy. However, the demographic impact is less well understood. This study aims to explore the dynamics of gene flow and population structure in eastern Iberia from the early to late medieval period through ancient DNA. Results Our comprehensive genomic analysis uncovers gene flow from various Mediterranean regions into Iberia before the Islamic period, supporting a pre-existing pan-Mediterranean homogenization phenomenon during the Roman Empire. North African ancestry is present but sporadic in late antiquity genomes but becomes consolidated during the Islamic period. We uncover one of the earliest dated Islamic burials in Spain, which shows high levels of consanguinity. For the first time, we also demonstrate the persistence of North African ancestry in a Christian cemetery until the seventeenth century, in addition to evidence of slave trafficking from North Africa. Conclusions This study reveals the complex interaction between political events and cultural shifts that influenced the population of eastern Iberia. It highlights the existence of a slave trade, underscores the low impact of the Reconquista in the genetic landscape, and shows the lasting impact of post-medieval events, such as the Expulsion of the Moriscos in 1609 CE, on the region’s genetic and cultural landscape, through mass population displacement and replacement.

neurosciencenews.com/dna-methy

Of *course* we have "abnormal" methylation of certain genes. /s

That aside, this article appeared relatively low on ableist language. My biggest reason for sharing it:

"Notably, immune activation and exposure to stress hormones are known to alter neuronal activity in the dorsal raphe (DR, a region of the brain involved in serotonin signaling), contributing to ASD development."

#ActuallyAutistic
#autism
#AutismResearch
#genetics
#methylation
@actuallyautistic

Neuroscience News · DNA Methylation in Serotonin Center Offers New Clues to Autism - Neuroscience NewsNeuroscience News provides research news for neuroscience, neurology, psychology, AI, brain science, mental health, robotics and cognitive sciences.

Here's the thing about rainbow lorikeets. They are endemic across the east coast of Australia. From the tip of Cape York down to somewhere in Victoria. At any given point, rainbow lorikeets can easily and successfully breed with their neighbours. BUT! Take a rainbow lorikeet from Cairns and put it with a sexy lorikeet from Sydney, and they will not produce viable offspring. I can't remember what it's called, genetic drift or something.

This random fact brought to you by the following sponsors:
* The rainbow lorikeets making a noise outside my window
* Autism
* Absolut vodka

I love youse all!
#WildOz #Birds #Genetics

Continued thread

Good news from @npr, as shared by our @ScienceDesk. A baby born in Philadelphia last August with a life-threatening genetic disorder was successfully treated with a gene-editing infusion developed using CRISPR technology. His genetic defect appears to have been fixed, at least partially reversing his condition.

npr.org/sections/shots-health-