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ma𝕏pool<p>Kaifosh, P., Reardon, T.R. &amp; CTRL-labs at Reality Labs. A generic non-invasive neuromotor interface for human-computer interaction. Nature (2025). <a href="https://doi.org/10.1038/s41586-025-09255-w" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1038/s41586-025-092</span><span class="invisible">55-w</span></a></p><p><a href="https://www.nature.com/articles/s41586-025-09255-w" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41586-025</span><span class="invisible">-09255-w</span></a></p><p>The sEMG decoding models performed well across people without person-specific training or calibration.</p><p><a href="https://mathstodon.xyz/tags/EMG" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>EMG</span></a> <a href="https://mathstodon.xyz/tags/HCI" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>HCI</span></a> <a href="https://mathstodon.xyz/tags/BMI" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>BMI</span></a> <a href="https://mathstodon.xyz/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a></p>
Nonya Bidniss :CIAverified:<p>Neuroscientists analyzed the brain tissue of people with Alzheimer’s disease and found that the sticky plaques of amyloid protein that are a hallmark of the disease had high concentrations of lithium, while it was depleted in the rest of the brain. The researchers hypothesized that lithium naturally exists in our bodies as part of a carefully calibrated ecosystem of metal ions. In Alzheimer’s disease, amyloid plaques sequester this freely available lithium, preventing it from being used in various neural processes. This process could lead to downstream symptoms of Alzheimer’s, like memory loss and cognitive decline.</p><p>Researchers then identified a compound called lithium orotate that can bolster natural levels of lithium without getting trapped by amyloid plaques. In studies of adult mice engineered to have Alzheimer’s-like symptoms, adding a low dose of lithium orotate to their drinking water prevented the development of plaques and completely reversed memory loss in mice. “It seems to somehow turn back the clock,” the paper’s senior author, Bruce Yankner, told The Boston Globe.</p><p>Scientists hope that this paper will breathe new life into the search for a cure for Alzheimer’s disease and open up new questions about the role of lithium in the brain. “[Lithium] powers our phones, laptops, and electric vehicles,” Yankner tells Science. “My guess is the brain might have utilized this unique electrochemistry before we did.” <a href="https://infosec.exchange/tags/alzheimers" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>alzheimers</span></a> <a href="https://infosec.exchange/tags/lithium" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lithium</span></a> <a href="https://infosec.exchange/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://infosec.exchange/tags/medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicine</span></a> <br>Paywall <a href="https://www.science.org/content/article/could-lithium-stave-alzheimer-s-disease" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">science.org/content/article/co</span><span class="invisible">uld-lithium-stave-alzheimer-s-disease</span></a><br>Paywall <a href="https://www.bostonglobe.com/2025/08/06/metro/alzheimers-treatment-harvard-lithium-deficiency-plaques/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">bostonglobe.com/2025/08/06/met</span><span class="invisible">ro/alzheimers-treatment-harvard-lithium-deficiency-plaques/</span></a> <br>Paywall <a href="https://www.nature.com/articles/d41586-025-02471-4" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/d41586-025</span><span class="invisible">-02471-4</span></a> <br>No paywall <a href="https://archive.is/LB5Ps" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">archive.is/LB5Ps</span><span class="invisible"></span></a></p>
Robert Roy Britt<p>With age, almost all humans deal with decline in memory and other <a href="https://me.dm/tags/brain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>brain</span></a> functions. But the minds of some people in their 80s and beyond function as though they were decades younger. Scientists have been studying these superagers for 25 years, testing their memory skills and autopsying their brains when they die. Two things stand out: Not all superagers do all the healthy things you might expect, but nearly all of them are highly social. <a href="https://medium.com/wise-well/secrets-of-remarkable-superager-brains-revealed-1a2ef69bc752" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">medium.com/wise-well/secrets-o</span><span class="invisible">f-remarkable-superager-brains-revealed-1a2ef69bc752</span></a> <a href="https://me.dm/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://me.dm/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a></p>
Dan Goodman<p>Spiking neural networks people, this message is for you! </p><p>The annual SNUFA workshop is now open for abstract submission (deadline Sept 26) and (free) registration. This year's speakers include Elisabetta Chicca, Jason Eshraghian, Tomoki Fukai, Chengcheng Huang, and... you?</p><p><a href="https://snufa.net/2025/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">snufa.net/2025/</span><span class="invisible"></span></a></p><p>Please boost!</p><p><a href="https://neuromatch.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://neuromatch.social/tags/computationalneuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>computationalneuroscience</span></a> <a href="https://neuromatch.social/tags/SpikingNeuralNetworks" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SpikingNeuralNetworks</span></a></p>
Science | The Guardian<p>Summer picks: Where do our early childhood memories go? – podcast <a href="https://www.theguardian.com/science/audio/2025/aug/07/summer-picks-where-do-our-early-childhood-memories-go-podcast" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">theguardian.com/science/audio/</span><span class="invisible">2025/aug/07/summer-picks-where-do-our-early-childhood-memories-go-podcast</span></a> <a href="https://halo.nu/tags/Children" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Children</span></a>'shealth <a href="https://halo.nu/tags/Medicalresearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Medicalresearch</span></a> <a href="https://halo.nu/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neuroscience</span></a> <a href="https://halo.nu/tags/Psychology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Psychology</span></a> <a href="https://halo.nu/tags/Children" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Children</span></a> <a href="https://halo.nu/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Science</span></a> <a href="https://halo.nu/tags/Memory" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Memory</span></a></p>
Neurofrontiers<p>Hey Fedi, I need some help. Lately, I’ve been facing some tough challenges in my job search and despite all my efforts, I haven’t been able to land something sustainable yet. </p><p>I have a PhD in computational neuroscience, with experience in time-series analysis and whole-brain simulations. I have teaching experience and in parallel to my PhD, I’ve been running a neuroscience blog (<a href="https://neurofrontiers.blog" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">neurofrontiers.blog</span><span class="invisible"></span></a>) for the past five years. This is my LinkedIn profile: <a href="https://www.linkedin.com/in/dr-cristiana-dimulescu-8a3a2b15b/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">linkedin.com/in/dr-cristiana-d</span><span class="invisible">imulescu-8a3a2b15b/</span></a></p><p>I’m looking for jobs either locally in Berlin (Germany) or remotely.</p><p>So far, I’ve been focused on data science roles, because that’s where the hard skills from my PhD would fit, but I’m open to exploring other opportunities, particularly as a medical science liaison or scientific writer. </p><p>If you know of any permanent or freelance opportunities, please let me know. Thanks a lot!</p><p>Edit: thank you so much to everyone who boosted this and reached out! Still not out of the woods yet, but the support gave me some much-needed hope. Thank you!</p><p><a href="https://neuromatch.social/tags/FediHire" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FediHire</span></a> <a href="https://neuromatch.social/tags/GetFediHired" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>GetFediHired</span></a> <a href="https://neuromatch.social/tags/DataScience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DataScience</span></a> <a href="https://neuromatch.social/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neuroscience</span></a> <a href="https://neuromatch.social/tags/SciComm" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SciComm</span></a> <a href="https://neuromatch.social/tags/JobSearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>JobSearch</span></a> <a href="https://neuromatch.social/tags/CommunitySupport" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CommunitySupport</span></a> <a href="https://neuromatch.social/tags/hired" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hired</span></a></p>
The Transmitter<p>We want to hear from you! <span class="h-card" translate="no"><a href="https://mastodon.social/@thetransmitter" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>thetransmitter</span></a></span> and <span class="h-card" translate="no"><a href="https://neuromatch.social/@neuromatch" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>neuromatch</span></a></span> are teaming up to better understand how to support early-career researchers. Make sure your voice is heard. <br><a href="https://www.thetransmitter.org/early-career-researchers/what-kinds-of-support-do-early-career-researchers-need/?utm_source=mastodon&amp;utm_medium=org-social&amp;utm_campaign=20250804-ecr-neuromatch-survey" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">thetransmitter.org/early-caree</span><span class="invisible">r-researchers/what-kinds-of-support-do-early-career-researchers-need/?utm_source=mastodon&amp;utm_medium=org-social&amp;utm_campaign=20250804-ecr-neuromatch-survey</span></a></p><p><a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a></p>
Ankur Sinha "FranciscoD"<p>The <a href="https://fosstodon.org/tags/NeuroFedora" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>NeuroFedora</span></a> team has changed how it packages software for users. We now prioritise software that cannot easily be installed from upstream forges (like PyPi) for inclusion as <a href="https://fosstodon.org/tags/rpm" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>rpm</span></a> packages into <span class="h-card" translate="no"><a href="https://fosstodon.org/@fedora" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>fedora</span></a></span> . Software that can be easily installed is tested to ensure that it functions on all the <a href="https://fosstodon.org/tags/Python" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Python</span></a> versions supported by any Fedora release.</p><p>Read more here:</p><p><a href="https://neuroblog.fedoraproject.org/2025/08/02/packaging-changes-at-neurofedora.html" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">neuroblog.fedoraproject.org/20</span><span class="invisible">25/08/02/packaging-changes-at-neurofedora.html</span></a></p><p>The Comp Neuro Lab has also been dropped.</p><p><a href="https://fosstodon.org/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neuroscience</span></a> <a href="https://fosstodon.org/tags/ComputationalNeuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ComputationalNeuroscience</span></a> <a href="https://fosstodon.org/tags/FOSS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FOSS</span></a> <a href="https://fosstodon.org/tags/Linux" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Linux</span></a> <a href="https://fosstodon.org/tags/Distributions" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Distributions</span></a></p>
Ian<p>Interview with Pim Van Lommel.</p><p><a href="https://mastodon.online/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a> <a href="https://mastodon.online/tags/consciousness" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>consciousness</span></a> <a href="https://mastodon.online/tags/nde" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>nde</span></a> <a href="https://mastodon.online/tags/death" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>death</span></a> <a href="https://mastodon.online/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://mastodon.online/tags/philosophy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>philosophy</span></a> <a href="http://youtube.com/watch?v=pVlgzjpTwxo&amp;feature=youtu.be" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">http://</span><span class="ellipsis">youtube.com/watch?v=pVlgzjpTwx</span><span class="invisible">o&amp;feature=youtu.be</span></a> <a href="http://shojiwax.com/2025/08/02/interview-with-pim-van-lommel/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">http://</span><span class="ellipsis">shojiwax.com/2025/08/02/interv</span><span class="invisible">iew-with-pim-van-lommel/</span></a></p>
Dan Goodman<p>New preprint with <span class="h-card" translate="no"><a href="https://neuromatch.social/@marcusghosh" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>marcusghosh</span></a></span> on how neural network architecture shapes function. We explored a wide range of architectures, and a family of tasks with components of navigation, decision making under uncertainty, multimodal integration and memory. Performance better explained by "computational traits" like sensitivity and memory, than by architectural features. </p><p><a href="https://www.biorxiv.org/content/10.1101/2025.07.28.667142v1" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">biorxiv.org/content/10.1101/20</span><span class="invisible">25.07.28.667142v1</span></a></p><p><a href="https://neuromatch.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://neuromatch.social/tags/compneuro" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>compneuro</span></a> <a href="https://neuromatch.social/tags/computationalneuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>computationalneuroscience</span></a></p>
Nonilex<p>The <a href="https://masto.ai/tags/Musk" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Musk</span></a> company raised $650 million in its latest funding round last month. It began human trials in 2024 on its <a href="https://masto.ai/tags/brain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>brain</span></a> implant after resolving <a href="https://masto.ai/tags/safety" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>safety</span></a> concerns flagged by the <a href="https://masto.ai/tags/US" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>US</span></a> <a href="https://masto.ai/tags/FDA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FDA</span></a>, which had initially rejected <a href="https://masto.ai/tags/Neuralink" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neuralink</span></a>'s application in 2022.</p><p>According to the company, 5 patients with severe <a href="https://masto.ai/tags/paralysis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>paralysis</span></a> are currently using its device to control digital &amp; physical tools with their thoughts.</p><p><a href="https://masto.ai/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a> <a href="https://masto.ai/tags/tech" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tech</span></a> <a href="https://masto.ai/tags/medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicine</span></a> <a href="https://masto.ai/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://masto.ai/tags/UK" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>UK</span></a></p>
Nonilex<p>The <a href="https://masto.ai/tags/Musk" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Musk</span></a> company is partnering with the University College London Hospitals trust [<a href="https://masto.ai/tags/UCLH" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>UCLH</span></a>] &amp; Newcastle Hospitals to conduct the study, it said in a post on X.</p><p><a href="https://masto.ai/tags/Neuralink" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neuralink</span></a> said patients living with <a href="https://masto.ai/tags/paralysis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>paralysis</span></a> due to conditions such as spinal cord injury &amp; a nervous system disease called Amyotrophic Lateral Sclerosis (<a href="https://masto.ai/tags/ALS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ALS</span></a>) qualify to participate in the study.</p><p><a href="https://masto.ai/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a> <a href="https://masto.ai/tags/tech" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tech</span></a> <a href="https://masto.ai/tags/medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicine</span></a> <a href="https://masto.ai/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://masto.ai/tags/UK" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>UK</span></a></p>
Nonilex<p><a href="https://masto.ai/tags/Musk" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Musk</span></a>'s <a href="https://masto.ai/tags/Neuralink" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neuralink</span></a> to test <a href="https://masto.ai/tags/brain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>brain</span></a> chips in clinical study in <a href="https://masto.ai/tags/UK" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>UK</span></a></p><p><a href="https://masto.ai/tags/ElonMusk" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ElonMusk</span></a>'s brain implant company Neuralink said on Thursday it will launch a clinical study in Great <a href="https://masto.ai/tags/Britain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Britain</span></a> to test how its chips can enable patients with severe <a href="https://masto.ai/tags/paralysis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>paralysis</span></a> to control digital &amp; physical tools with their thoughts.</p><p><a href="https://masto.ai/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a> <a href="https://masto.ai/tags/tech" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tech</span></a> <a href="https://masto.ai/tags/medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicine</span></a> <a href="https://masto.ai/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <br><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/musks-neuralink-test-brain-chips-clinical-study-great-britain-2025-07-31/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">reuters.com/business/healthcar</span><span class="invisible">e-pharmaceuticals/musks-neuralink-test-brain-chips-clinical-study-great-britain-2025-07-31/</span></a></p>
mnl mnl mnl mnl mnl<p>Fellow multilingual people, how strongly do you:</p><p>1) “think” in a certain language<br>2) use a different thinking language<br>3) feel that you have different thoughts based on the language you think in<br>4) how related is the language you speak to the way you think ?</p><p>Also people who are in the field (cognitive neuroscience? Linguistics?), what’s some good current material on the topic?</p><p>I know it’s a lot of weird questions that are probably impossible to answer.</p><p>FWIW I can’t really pinpoint if I think in a certain language. I do think my personality changes a bit or rather, I feel like my personality changes (for example the cliche of the rude French person with a proclivity for sexualized language). Certain things are easier to express in a certain language and thus influence the recursive thinking-speaking/writing loop (ever tried to explain something technical in French, or do Deleuze style poetic rambling in English?), but it feels like an externality.</p><p><a href="https://hachyderm.io/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://hachyderm.io/tags/linguistics" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>linguistics</span></a> <a href="https://hachyderm.io/tags/language" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>language</span></a></p>
Yohan John 🤖🧠<p>Here's the next part of my series on neuroscience and hyperreality.</p><p><a href="https://open.substack.com/pub/yohanjohn/p/neuroscience-should-not-blur-the" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">open.substack.com/pub/yohanjoh</span><span class="invisible">n/p/neuroscience-should-not-blur-the</span></a></p><p><a href="https://fediscience.org/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a></p>
Jalal Khawaldeh<p>We all share the same intricate blueprint of the head—skull, brain, senses—yet each mind crafts a unique universe. How do identical structures spawn such diverse thoughts, beliefs, and identities? What sparks the symphony of individuality? <a class="hashtag" rel="nofollow noopener" href="https://bsky.app/search?q=%23Consciousness" target="_blank">#Consciousness</a> <a class="hashtag" rel="nofollow noopener" href="https://bsky.app/search?q=%23awareness" target="_blank">#awareness</a> <a class="hashtag" rel="nofollow noopener" href="https://bsky.app/search?q=%23Neuroscience" target="_blank">#Neuroscience</a> <a class="hashtag" rel="nofollow noopener" href="https://bsky.app/search?q=%23Humanity" target="_blank">#Humanity</a></p>
Redish Lab<p>We're still doing science!</p><p>Kocharian, A., Redish, A.D. &amp; Rothwell, P.E. Individual differences in decision-making shape how mesolimbic dopamine regulates choice confidence and change-of-mind. Nature Neuroscience (2025). </p><p><a href="https://www.nature.com/articles/s41593-025-02015-z" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41593-025</span><span class="invisible">-02015-z</span></a></p><p>One of many exciting results: When mice change their mind about a choice (quitting out of the wait zone on our <a href="https://neuromatch.social/tags/RestaurantRow" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>RestaurantRow</span></a> task), there is a dip in dopamine, even though there is no new information provided. Creating such a dip with optogenetic inhibition increases the likelihood of quitting.</p><p><a href="https://neuromatch.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a></p><p>Also available as a preprint on biorxiv. <a href="https://www.biorxiv.org/content/10.1101/2024.09.16.613237v1" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">biorxiv.org/content/10.1101/20</span><span class="invisible">24.09.16.613237v1</span></a></p>
ma𝕏pool<p>What is the biochemical origin of the need to sleep? </p><p>Are changes in metabolites, cellular behavior, neuronal firing patterns and all the rest of it the signals that tell you that you need sleep? Or are they just things that are brought on by the need for sleep, and thus downstream of something else? </p><p>“electrons flow through the respiratory chains of the respective feedback controllers like sand in the hourglass that determines when balance must be restored”</p><p>Derek Lowe: It All Comes Down to the Mitochondria <a href="https://www.science.org/content/blog-post/it-all-comes-down-mitochondria" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">science.org/content/blog-post/</span><span class="invisible">it-all-comes-down-mitochondria</span></a></p><p>paper: Mitochondrial origins of the pressure to sleep<br><a href="https://www.nature.com/articles/s41586-025-09261-y" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41586-025</span><span class="invisible">-09261-y</span></a></p><p><a href="https://mathstodon.xyz/tags/biochemistry" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biochemistry</span></a> <a href="https://mathstodon.xyz/tags/sleep" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>sleep</span></a> <a href="https://mathstodon.xyz/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://mathstodon.xyz/tags/metabolism" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>metabolism</span></a></p>
Björn Brembs<p>New preprint out!</p><p>Beyond picking and choosing: The emerging neurobiology of decision-making</p><p><a href="https://doi.org/10.5281/zenodo.16571152" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">doi.org/10.5281/zenodo.16571152</span><span class="invisible"></span></a></p><p>Part of an upcoming special issue with contributors from this conference:</p><p><a href="https://philosophie.univie.ac.at/news-events/nachrichten-news-events/detailansicht-news-events/news/interdisciplinary-conference-free-will-new-perspectives-from-philosophy-biology-and-neuroscience/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">philosophie.univie.ac.at/news-</span><span class="invisible">events/nachrichten-news-events/detailansicht-news-events/news/interdisciplinary-conference-free-will-new-perspectives-from-philosophy-biology-and-neuroscience/</span></a></p><p>My talk was recorded:<br><a href="https://youtu.be/Yabf5Y1KQ68?si=OyTSx5zSBW5jKCOg" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">youtu.be/Yabf5Y1KQ68?si=OyTSx5</span><span class="invisible">zSBW5jKCOg</span></a></p><p>as was the kick-off presentation of organizer Anne Sophie Meincke:</p><p><a href="https://youtu.be/AHGRp9q5wv4?si=mx-GwneMDcmqwqvq" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">youtu.be/AHGRp9q5wv4?si=mx-Gwn</span><span class="invisible">eMDcmqwqvq</span></a></p><p><a href="https://mastodon.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biology</span></a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://mastodon.social/tags/freewill" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>freewill</span></a></p>
Ben Waber<p>Next was an excellent talk by <span class="h-card" translate="no"><a href="https://fediscience.org/@caterinagratton" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>caterinagratton</span></a></span> on "precision" in fMRI at the UW eScience Institute <a href="https://www.youtube.com/watch?v=W2TbMfJrwi4" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="">youtube.com/watch?v=W2TbMfJrwi4</span><span class="invisible"></span></a> (6/7) <a href="https://hci.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a></p>