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⛑️🩹♡ Sweetnee ♡🩹⛑️( question ) Since I've already asked about people Aoa's that are 10 and below I have another question who has a Aoa that involves teens basically 13 , 14 ect how did you figure it out ? Or what do you like about your aoa ? :tbl: ☆ :tl: ☆ :tgl: ☆ :tel: <a href="https://yiffy.pet/tags/map" rel="nofollow noopener" target="_blank">#map</a> <a href="https://yiffy.pet/tags/yap" rel="nofollow noopener" target="_blank">#yap</a>

Darth Aloha 🌺Tamil Harbor Yap, Micronesia October 1, 2018 <a href="https://pixelfed.social/discover/tags/sunset?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#sunset</a> <a href="https://pixelfed.social/discover/tags/photography?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#photography</a> <a href="https://pixelfed.social/discover/tags/puddle?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#puddle</a> <a href="https://pixelfed.social/discover/tags/reflection?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#reflection</a> <a href="https://pixelfed.social/discover/tags/yap?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#yap</a> <a href="https://pixelfed.social/discover/tags/micronesia?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#micronesia</a>

Julien DelpierreNew <a href="https://biologists.social/tags/mechanobiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#mechanobiology</a> paper on <a href="https://biologists.social/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#cancer</a> <a href="https://biologists.social/tags/microenvironment" class="mention hashtag" rel="nofollow noopener" target="_blank">#microenvironment</a>. The authors show that cancer-associated <a href="https://biologists.social/tags/fibroblasts" class="mention hashtag" rel="nofollow noopener" target="_blank">#fibroblasts</a> (CAFs) compress tumors with actomyosin supracellular contractility supported by <a href="https://biologists.social/tags/fibronectin" class="mention hashtag" rel="nofollow noopener" target="_blank">#fibronectin</a> deposition. This induces <a href="https://biologists.social/tags/YAP" class="mention hashtag" rel="nofollow noopener" target="_blank">#YAP</a> nuclear exit in cancer cells, limits cancer growth, and induces tumor reorganization.<a href="https://www.nature.com/articles/s41467-023-42382-4" rel="nofollow noopener" translate="no" target="_blank">https://www.nature.com/articles/s41467-023-42382-4</a>

The EMBO Journal<a href="https://sciencemastodon.com/tags/YAP" class="mention hashtag" rel="nofollow noopener" target="_blank">#YAP</a>/#BRD4-controlled ROR1 promotes tumor-initiating cells and <a href="https://sciencemastodon.com/tags/hyperproliferation" class="mention hashtag" rel="nofollow noopener" target="_blank">#hyperproliferation</a> in <a href="https://sciencemastodon.com/tags/pancreaticcancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#pancreaticcancer</a>Masaya Yamazaki et al show that <a href="https://sciencemastodon.com/tags/ROR1" class="mention hashtag" rel="nofollow noopener" target="_blank">#ROR1</a> marks an aggressive partial <a href="https://sciencemastodon.com/tags/EMT" class="mention hashtag" rel="nofollow noopener" target="_blank">#EMT</a> cell cluster and enhances <a href="https://sciencemastodon.com/tags/PDAC" class="mention hashtag" rel="nofollow noopener" target="_blank">#PDAC</a> proliferation via c-<a href="https://sciencemastodon.com/tags/Myc" class="mention hashtag" rel="nofollow noopener" target="_blank">#Myc</a>/#E2F/#AURKB signaling<a href="https://www.embopress.org/doi/10.15252/embj.2022112614" rel="nofollow noopener" target="_blank">https://www.embopress.org/doi/10.15252/embj.2022112614</a>

The EMBO JournalEMBO Journal Issue 4/23: - Commentary on <a href="https://sciencemastodon.com/tags/creativity" class="mention hashtag" rel="nofollow noopener" target="_blank">#creativity</a> needs in research - <a href="https://sciencemastodon.com/tags/Degron" class="mention hashtag" rel="nofollow noopener" target="_blank">#Degron</a> recognition in orphan complex subunits by CLR4-DCAF12 E3 <a href="https://sciencemastodon.com/tags/ubiquitin" class="mention hashtag" rel="nofollow noopener" target="_blank">#ubiquitin</a> <a href="https://sciencemastodon.com/tags/ligase" class="mention hashtag" rel="nofollow noopener" target="_blank">#ligase</a> - <a href="https://sciencemastodon.com/tags/Plasmamembrane" class="mention hashtag" rel="nofollow noopener" target="_blank">#Plasmamembrane</a> topography of <a href="https://sciencemastodon.com/tags/IgM" class="mention hashtag" rel="nofollow noopener" target="_blank">#IgM</a> <a href="https://sciencemastodon.com/tags/Bcell" class="mention hashtag" rel="nofollow noopener" target="_blank">#Bcell</a> receptors - <a href="https://sciencemastodon.com/tags/YAP" class="mention hashtag" rel="nofollow noopener" target="_blank">#YAP</a> roles and regulation in <a href="https://sciencemastodon.com/tags/tumorigenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#tumorigenesis</a> - <a href="https://sciencemastodon.com/tags/Brassinosteroid" class="mention hashtag" rel="nofollow noopener" target="_blank">#Brassinosteroid</a> interplay with <a href="https://sciencemastodon.com/tags/katanin" class="mention hashtag" rel="nofollow noopener" target="_blank">#katanin</a> <a href="https://sciencemastodon.com/tags/microtubule" class="mention hashtag" rel="nofollow noopener" target="_blank">#microtubule</a> severingCover by Satarupa Bhaduri, Analine Aguayo, Sonya Neal et al <a href="https://www.embopress.org/toc/14602075/2023/42/4" rel="nofollow noopener" target="_blank">https://www.embopress.org/toc/14602075/2023/42/4</a>

The EMBO JournalUnusual <a href="https://sciencemastodon.com/tags/ubiquitin" class="mention hashtag" rel="nofollow noopener" target="_blank">#ubiquitin</a> <a href="https://sciencemastodon.com/tags/ligase" class="mention hashtag" rel="nofollow noopener" target="_blank">#ligase</a> interplay in <a href="https://sciencemastodon.com/tags/Hippo" class="mention hashtag" rel="nofollow noopener" target="_blank">#Hippo</a> <a href="https://sciencemastodon.com/tags/signaling" class="mention hashtag" rel="nofollow noopener" target="_blank">#signaling</a>: Bin Zhao, Xin-Hua Feng and colleagues Zhejiang University show that <a href="https://sciencemastodon.com/tags/HERC3" class="mention hashtag" rel="nofollow noopener" target="_blank">#HERC3</a> blocks <a href="https://sciencemastodon.com/tags/YAP" class="mention hashtag" rel="nofollow noopener" target="_blank">#YAP</a>/#TAZ recognition and degradation via <a href="https://sciencemastodon.com/tags/SCF" class="mention hashtag" rel="nofollow noopener" target="_blank">#SCF</a>-<a href="https://sciencemastodon.com/tags/betaTrCP" class="mention hashtag" rel="nofollow noopener" target="_blank">#betaTrCP</a> independent of its own E3 activity <a href="https://www.embopress.org/doi/10.15252/embj.2022111549" rel="nofollow noopener" target="_blank">https://www.embopress.org/doi/10.15252/embj.2022111549</a>

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