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Matt Willemsen<p>AI traces mysterious metastatic cancers to their source<br><a href="https://www.nature.com/articles/d41586-024-01110-8" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/d41586-024</span><span class="invisible">-01110-8</span></a> <a href="https://mastodon.social/tags/AI" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AI</span></a> <a href="https://mastodon.social/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancer</span></a> <a href="https://mastodon.social/tags/metastasis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>metastasis</span></a> <a href="https://mastodon.social/tags/origins" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>origins</span></a> <a href="https://mastodon.social/tags/PrimaryTumour" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PrimaryTumour</span></a></p>
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#metastasis
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PLOS Biology<p>Non-canonical role of the E3 <a href="https://fediscience.org/tags/ubiquitin" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ubiquitin</span></a> ligase FBXO3 in PI3K-induced <a href="https://fediscience.org/tags/BreastCancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>BreastCancer</span></a> <a href="https://fediscience.org/tags/metastasis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>metastasis</span></a>: FBXO3 binds & protects USP4 from DNPEP-mediated degradation, resulting in Twist1 protein stabilization & increased <a href="https://fediscience.org/tags/tumor" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tumor</span></a> metastasis <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PLOSBiology</span></a> <a href="https://plos.io/3twkOan" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3twkOan</span><span class="invisible"></span></a></p>
Amelia Glazier<p>Hi <a href="https://biologists.social/tags/ScienceMastodon" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceMastodon</span></a>! The next Research Highlight from JCS features one of my favorite model organisms... <a href="https://biologists.social/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>zebrafish</span></a>! Check out this study from Juma Ward and Paul Martin at the University of Bristol taking advantage of transparent zebrafish embryos to image extravasation of circulating tumor cells. They explore the mechanism behind an emerging link between thrombosis and <a href="https://biologists.social/tags/metastasis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>metastasis</span></a> in <a href="https://biologists.social/tags/cancerbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancerbio</span></a>.</p><p>Platelets and immune cells are accomplices in cancer cell extravasation<br><a href="https://journals.biologists.com/jcs/article/136/18/e136_e1802/330690/Platelets-and-immune-cells-are-accomplices-in" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">journals.biologists.com/jcs/ar</span><span class="invisible">ticle/136/18/e136_e1802/330690/Platelets-and-immune-cells-are-accomplices-in</span></a></p>
Furqan Shah<p><a href="https://mstdn.science/tags/Magnesium" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Magnesium</span></a> <a href="https://mstdn.science/tags/whitlockite" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>whitlockite</span></a> formation in the alveolar <a href="https://mstdn.science/tags/bone" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>bone</span></a>, with <a href="https://mstdn.science/tags/bisphosphonate" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>bisphosphonate</span></a> exposure and <a href="https://mstdn.science/tags/osteolytic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>osteolytic</span></a> <a href="https://mstdn.science/tags/skeletal" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>skeletal</span></a> <a href="https://mstdn.science/tags/metastasis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>metastasis</span></a>. Scanning electron microscopy, Micro-Raman spectroscopy, and energy dispersive X-ray spectroscopy revealed Mg-rich, rhomboidal nodules (~200 nm to ~2.4 µm) within the lacuno-canalicular space. Mg-whitlockite formation within <a href="https://mstdn.science/tags/osteocyte" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>osteocyte</span></a> lacunae is multifactorial in <a href="https://mstdn.science/tags/nature" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>nature</span></a> and suggests altered bone <a href="https://mstdn.science/tags/biomineralization" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biomineralization</span></a>.</p><p>Read more:<br><a href="https://doi.org/10.1016/j.micron.2023.103441" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1016/j.micron.2023.</span><span class="invisible">103441</span></a></p><p><a href="https://mstdn.science/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biology</span></a> <a href="https://mstdn.science/tags/pathology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pathology</span></a></p>
Ute Jungwirth<p>An introduction - I am an Assistant Professor @ University of Bath (UK) with a <a href="https://mstdn.science/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a> team focusing on how tumour cells interact with its surrounding non-cancerous cells (we love <a href="https://mstdn.science/tags/fibroblasts" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>fibroblasts</span></a>, and sometimes we hate them). These interactions can impact tumour progression, <a href="https://mstdn.science/tags/metastasis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>metastasis</span></a> & therapy response. <br>We also test novel anticancer compounds from our medicinal/biological chemistry colleagues. Furthermore, I teach the next generation in <a href="https://mstdn.science/tags/pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pharmacology</span></a>, <a href="https://mstdn.science/tags/toxicology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>toxicology</span></a>, <a href="https://mstdn.science/tags/cancerresearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancerresearch</span></a>.</p>
IT News<p>Meta removes Facebook account mandate from Quest VR—but is that enough? - Enlarge / Let's just see who you really are under that mask of a positi... - <a href="https://arstechnica.com/?p=1865119" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="">arstechnica.com/?p=1865119</span><span class="invisible"></span></a> <a href="https://schleuss.online/tags/gaming" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>gaming</span></a>&culture <a href="https://schleuss.online/tags/facebookening" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>facebookening</span></a> <a href="https://schleuss.online/tags/oculusquest" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>oculusquest</span></a> <a href="https://schleuss.online/tags/metastasis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>metastasis</span></a> <a href="https://schleuss.online/tags/metaquest" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>metaquest</span></a> <a href="https://schleuss.online/tags/features" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>features</span></a> <a href="https://schleuss.online/tags/facebook" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>facebook</span></a> <a href="https://schleuss.online/tags/meta" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>meta</span></a></p>
Aurélien Grosdidier ✅<p><a href="https://mastodon.social/tags/laser" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Laser</span></a> Destroys <a href="https://mastodon.social/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer</span></a> Cells Circulating in the Blood | <a href="https://mastodon.social/tags/melanoma" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>melanoma</span></a> <a href="https://mastodon.social/tags/metastasis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>metastasis</span></a> <a href="https://spectrum.ieee.org/the-human-os/biomedical/diagnostics/laser-destroys-cancer-cells-circulating-in-the-blood" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">spectrum.ieee.org/the-human-os</span><span class="invisible">/biomedical/diagnostics/laser-destroys-cancer-cells-circulating-in-the-blood</span></a></p>
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