Giuseppe Michieli<p>The <a href="https://mstdn.science/tags/virus" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>virus</span></a> <a href="https://mstdn.science/tags/sequences" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>sequences</span></a> are HA clade 2.3.4.4b HPAI A(<a href="https://mstdn.science/tags/H5N1" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>H5N1</span></a>) with each individual gene segment closely related to viruses detected in dairy <a href="https://mstdn.science/tags/cattle" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cattle</span></a> available from USDA testing in Texas. <br>...<br>both cattle and <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>human</span></a> sequences maintain primarily avian genetic characteristics and for the most part lack changes that would make them better adapted to infect <a href="https://mstdn.science/tags/mammals" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mammals</span></a>. The genome for the human isolate had one change (<a href="https://mstdn.science/tags/PB2" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PB2</span></a> <a href="https://mstdn.science/tags/E627K" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>E627K</span></a>) that is known to be associated with viral adaptation to mammalian hosts</p>