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first10em.com/research-roundup

"my plan is to use steroids in patients with severe community acquired pneumonia going to the ICU who look like the CAPE-COD patients"
One of the more interesting articles review on this Paper Of The Month edition
By @first10em
#FOAMed #emergencymedicine #FOAMcc #emergencyphysician

First10EMResearch Roundup (July 2023) - First10EMThe July 2023 research roundup - interesting and important emergency medicine articles summarized and appaised

New #ICUOnePager about hemophagocytic lymphohistiocytosis (HLH) & macrophage activation syndrome (MAS).

This life threatening disease can be a challenge to diagnose & treat; multidisciplinary collaboration is essential!

This OnePager (in collab w/ @MithuRheum) covers the 🔑 points:
:antibody: etiology: primary vs secondary; infxn, rheum, malignancy, etc
🔬 diagnosis: Se/Sp of each criteria
💊 treatment: algorithmic approach

#FOAMed #FOAMcc #MedMastodon

More at onepagericu.com/hlh

Well, since there are so many new people here, maybe it’s time for a re-#introduction.

I’m a pediatric gastroenterologist in 🇨🇦 with clinical interests in #intestinalfailure #CF and #nutrition. I’m also a program director and into all things #MedEd, especially #FOAMed. I co-host the @bowelsounds podcast and do social media for JPGN (not yet on Mastodon).

I’m loving the great sense of community here, and I’m here for all the great #MedMastodon #Gastrodon #MedEdadon people joining in droves!

Not that I don't love everyone who has come here on #MedMastodon but someone has to drag Dr. Sam Ghali (@EM_RESUS on Twitter) over here. It would be a huge loss not to have his weekly #FOAMed and #ECG cases.

I'm just a lab tech that had to do ECGs at my last job and I learned SO much from his tweets. I actually can tell when things are wrong now and can identify certain conditions. He's brilliant.

Someone has to have an in with him.

Continued thread

In addition to glucose effects. Don’t if been used in sepsis? Metformin toxicity is under diagnosed and should be considered in AKI/renal accumulation in an odd lactate situation. It is reversible and improves with filtration. It has potential to give a false impression of illness severity if not addressed. Mitochondrial inhibition was originally part of reason not ideal post MI for a few days. #medicine #FOAMed #science

So has been much debate on covid19 being a new disease (to a degree but also not, imo) and now consortium of researchers demonstrate that organs affected by covid19 inflammation don't have to be INFECTED directly. Tissue-specific tolerance is what drives whether or not covid provokes calamity. This could thus mean very real signal regarding dexamathasone medrxiv.org/content/10.1101/20 #medicine #FOAMed #medstatron #science #covid19

Vision is actually not that complicated. A single photon is absorbed by rhodopsin which is a seven fingered protein that lies in the retina. This causes a conformational change that allows an action potential. The cofactor is vitamin A #science #FOAMed